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Inside-out membrane vesicles isolated from HEK293 cells.
BSEP vesicles with an ATP/AMP ratio >10 are readily available from PharmTox.
BSEP mediated TCA transport:

Name: BSEP, Bile Salt Export Pump, ATP-binding cassette sub-family B member 11, ABCB11.
Diseases: inherited and drug-induced cholestasis.
BSEP substrates: taurocholate, pravastatin, taurolitocholyl 3-sulfate, conjugated monovalent bile salts.
BSEP is present in: canalicular plasma membrane of hepatocytes.
In stock: human, cat, and dog BSEP.
Available: mouse and rat BSEP.

For ordering information or product quotes please contact PharmTox.
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