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Inside-out membrane vesicles isolated from HEK293 cells.
BCRP vesicles with an ATP/AMP ratio >10 are readily available from PharmTox.
BCRP mediated E1S transport:

Name: BCRP, breast cancer resistance protein, ATP-binding cassette sub-family G member 2, ABCG2.
Diseases: - .
BCRP substrates: E1S, estrone-3-sulfate, methotrexate, irinotecan, pantoprazole, rosuvastatin, topotecan, chlorothiazide etc.
BCRP is present in: placenta, stem cells, prostate, small intestine, brain, colon, liver, mammary gland and kidney.
In stock: human BCRP.
Available: mouse and rat BCRP.

For ordering information or product quotes please contact PharmTox.
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